Imuniplant can influence disfunctional immune responses in elderly people
Major Gheorghe Giurgiu1, Prof. dr. Manole Cojocaru2
1Deniplant-Aide Sante Medical Center, Biomedicine, Bucharest, Romania
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2The Romanian Academy of Scientists
Titu Maiorescu University, Faculty of Medicine, Bucharest, Romania
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Background The immune system plays a vital role in keeping the body healthy by providing a fine balance between the elimination of invading pathogens and the maintenance of tolerance to healthy self-tissue. It is now evident that the gut microbiota has a profound effect on the host immune system and can affect autoimmune-related diseases. The interactions between the gut microbiota and host immunity are complex, dynamic and context-dependent. The gut microbiota and its metabolites have been shown to influence immune functions and immune homeostasis both locally and systemically. Antibiotic treatments, vaccinations and hygiene practices all can alter gut microbiota composition.
Objectives To demonstrate role of Imuniplant in the management of disfunctional immune responses. The direct modulation of gut microbiome that could diminish inflammatory responses and ameliorate adaptive immune responses is major pathway to stabilize immunosenescence.
Materials and methods Recent reports indicate that dysbiosis is increased in aging. Imuniplant modulation of the immune system has applications within the clinical setting, but can also have a role in the aging population, acting to reduce or delay the onset of immune-mediated chronic diseases. Ongoing research in this field will ultimately lead to a better understanding of the role of diet and Imuniplant in immune function and inflammation in elderly people.
Results A dysfunctional immune system can cause a whole range of pro-inflammatory conditions like impaired gut function, weakened responses to new infection. Imuniplant may restore the composition of the gut microbiome and introduce beneficial functions to gut microbial communities, resulting in amelioration or prevention of gut inflammation and other systemic diseases.
Conclusion The composition of the gut microbiota changes with age. The gut microbiota is considered to be a master regulator of immune homeostasis. Besides modifying the gut microbiota, Imuniplant modulates the immune system in elderly people
Keywords: aging, disfunctional immune responses, gut microbiota, immunomodulation, Imuniplant